Moxi V:
High Quality Data
Fast, Easy, and Secure Results
- Counting Thousands of Cells is More Accurate Than Imaging
- Fast Time to Result: <15 seconds Per Sample
- Obtain Accurate Counts Instead of Relative Estimates
- 21 CFR Part 11 Software Available for Compliance
- Differentiation of Cell Types in a Mixed Population
- Simple User Interface Usable by Any Lab Personnel
- Superior Characterization With Particle Size Resolution to 0.1µm
- Zero Instrument Maintenance, Cleaning, or Preparation Needed
- Coulter Principle Counting = Greater Reproducibility With CVs <5%
Unbeatable Viability Measurements
Don’t need the two fluorescence channels and flow cytometer-like capabilities of the Moxi GO II, but want some fluorescent capabilities for reliable viability measurements? We have you covered with our single 561nm/LP (Orange/Red) cell viability instrument in the Moxi V. Moxi V provides true cell viability counts with dyes like propidium iodide (PI), with 50-100x more cells counted compared to vision counters. Get precise cell characterization with CVs less than 5%, without the need for triplicates and a self-contained, easy to use, and affordable machine.
Applications Overview
The accuracy provided by the Moxi V allows for an unprecedented capability for true viability counting. High fluorescence sensitivity gives the ability to detect cells stained with propidium iodide (PI), which primes it for use in any workflow that requires reliable viability measurements like cell culture work, single cell genomics, PBMC analysis, and more.
Single Cell Genomics
PBMC Analysis
How it Works
ORFLO’s proprietary cell counting technology can count tens of thousands of cells in seconds, quickly providing best-in-class data. Normally, accuracy is negatively impacted by acquisition time. However, by leveraging the current gold standard Coulter Principle, we bring you both with no compromises to either. All of this in a self-contained, easy-to-use, and benchtop-sized instrument. The addition of orange fluorescence detection adds a second dimension to viability measurements that means the reliability of your viability measurements has never been better.
The core of our technology lies in what is most commonly referred to as the Coulter Principle. Put simply, we are using a gap between two electrodes to measure the change in voltage as a cell passes through it.
Through this change in voltage, we can accurately determine the volume and diameter of the cell that passed through (Detectable size range = 3µm-26µm for S+ cassettes; 4µm-35µm for M+ cassettes). Because of the precise nature of the Coulter Principle and our ability to monitor minute changes in electrical current rapidly and in real time, thousands of cells can be passed through the aperture and recorded/sized within seconds. These thousands of instances are placed into scatter plot that makes it easy to see the cells present in your sample and manipulate the data on our touch-screen interface.
We have revolutionized the industry by miniaturizing this Coulter Principle-based counting into a small disposable microfluidics cassettes. We have created a simple, effective, and self-contained way to get everything you need, with all of the speed and none of the bulk of other cell counters or flow cytometers. Just insert the cassette, pipette in a small amount of your precious sample, and let the microfluidics and our proprietary cell counting technology do the rest.
With our Moxi V system, we have coupled our cell counting technology with the ability to detect one 561nm/LP (Orange/Red) channel of fluorescence. Our 488nm laser and pin diode give better accuracy and detection capabilities compared to a vision-based counter. This combination gives you unbeatable benchtop power for obtaining true viability counts when working with any cell type stained with propidium iodide (PI).
